R-CRISPR: A Deep Learning Network to Predict Off-Target Activities with Mismatch, Insertion and Deletion in CRISPR-Cas9 System

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)—associated protein 9 (Cas9) system is a groundbreaking gene-editing tool, which has been widely adopted in biomedical research. However, the guide RNAs in CRISPR-Cas9 system may induce unwanted off-target activities and further a...

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Detalles Bibliográficos
Autores principales: Niu, Rui, Peng, Jiajie, Zhang, Zhipeng, Shang, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702036/
https://www.ncbi.nlm.nih.gov/pubmed/34946828
http://dx.doi.org/10.3390/genes12121878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702036/
https://www.ncbi.nlm.nih.gov/pubmed/34946828
http://dx.doi.org/10.3390/genes12121878

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