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R-CRISPR: A Deep Learning Network to Predict Off-Target Activities with Mismatch, Insertion and Deletion in CRISPR-Cas9 System

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)—associated protein 9 (Cas9) system is a groundbreaking gene-editing tool, which has been widely adopted in biomedical research. However, the guide RNAs in CRISPR-Cas9 system may induce unwanted off-target activities and further a...

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Detalles Bibliográficos
Autores principales:	Niu, Rui, Peng, Jiajie, Zhang, Zhipeng, Shang, Xuequn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702036/ https://www.ncbi.nlm.nih.gov/pubmed/34946828 http://dx.doi.org/10.3390/genes12121878

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