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Single Cell Sequencing of Induced Pluripotent Stem Cell Derived Retinal Ganglion Cells (iPSC-RGC) Reveals Distinct Molecular Signatures and RGC Subtypes

We intend to identify marker genes with differential gene expression (DEG) and RGC subtypes in cultures of human-induced pluripotent stem cell (iPSC)-derived retinal ganglion cells. Single-cell sequencing was performed on mature and functional iPSC-RGCs at day 40 using Chromium Single Cell 3’ V3 pro...

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Detalles Bibliográficos
Autores principales: Gudiseva, Harini V., Vrathasha, Vrathasha, He, Jie, Bungatavula, Devesh, O’Brien, Joan M., Chavali, Venkata R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702079/
https://www.ncbi.nlm.nih.gov/pubmed/34946963
http://dx.doi.org/10.3390/genes12122015