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Genetic Insights into the Impact of Complement in Alzheimer’s Disease

The presence of complement activation products at sites of pathology in post-mortem Alzheimer’s disease (AD) brains is well known. Recent evidence from genome-wide association studies (GWAS), combined with the demonstration that complement activation is pivotal in synapse loss in AD, strongly implic...

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Detalles Bibliográficos
Autores principales: Torvell, Megan, Carpanini, Sarah M., Daskoulidou, Nikoleta, Byrne, Robert A. J., Sims, Rebecca, Morgan, B. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702080/
https://www.ncbi.nlm.nih.gov/pubmed/34946939
http://dx.doi.org/10.3390/genes12121990