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Spironolactone Inhibits Cardiomyocyte Hypertrophy by Regulating the Ca(2+)/Calcineurin/p-NFATc3 Pathway
This study aimed to investigate the protective effect and molecular mechanism of spironolactone in isoproterenol-induced cardiomyocyte hypertrophy. In this study, primary cardiomyocytes were extracted from the heart of neonatal rats. After stable culture, they were processed with isoproterenol alone...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702305/ https://www.ncbi.nlm.nih.gov/pubmed/34956570 http://dx.doi.org/10.1155/2021/3843830 |