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Spironolactone Inhibits Cardiomyocyte Hypertrophy by Regulating the Ca(2+)/Calcineurin/p-NFATc3 Pathway

This study aimed to investigate the protective effect and molecular mechanism of spironolactone in isoproterenol-induced cardiomyocyte hypertrophy. In this study, primary cardiomyocytes were extracted from the heart of neonatal rats. After stable culture, they were processed with isoproterenol alone...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Zhang, Wenting, Na, Jingtao, Huo, Yanping, Wang, Yacheng, Liu, Ketong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702305/
https://www.ncbi.nlm.nih.gov/pubmed/34956570
http://dx.doi.org/10.1155/2021/3843830