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NR1D1 Deletion Induces Rupture-Prone Vulnerable Plaques by Regulating Macrophage Pyroptosis via the NF-κB/NLRP3 Inflammasome Pathway

Vulnerable plaque rupture is the main trigger of most acute cardiovascular events. But the underlying mechanisms responsible for the transition from stable to vulnerable plaque remain largely unknown. Nuclear receptor subfamily 1 group D member 1 (NR1D1), also known as REV-ERB α, is a nuclear recept...

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Detalles Bibliográficos
Autores principales: Wu, Zhinan, Liao, Fei, Luo, Guqing, Qian, Yuxuan, He, Xinjie, Xu, Wenyi, Ding, Song, Pu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702349/
https://www.ncbi.nlm.nih.gov/pubmed/34956438
http://dx.doi.org/10.1155/2021/5217572