Hydrogel contained valproic acid accelerates bone-defect repair via activating Notch signaling pathway in ovariectomized rats

The purpose was to observe whether valproic acid (VPA) has a positive effect on bone-defect repair via activating the Notch signaling pathway in an OVX rat model. The MC3T3-E1 cells were cocultured with VPA and induced to osteogenesis, and the osteogenic activity was observed by alkaline phosphatase...

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Detalles Bibliográficos
Autores principales: Tao, Zhou-Shan, Li, Tian-Lin, Xu, Hong-Guang, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Biomaterials Synthesis and Characterization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702411/
https://www.ncbi.nlm.nih.gov/pubmed/34940936
http://dx.doi.org/10.1007/s10856-021-06627-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702411/
https://www.ncbi.nlm.nih.gov/pubmed/34940936
http://dx.doi.org/10.1007/s10856-021-06627-2

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