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Hydrogel contained valproic acid accelerates bone-defect repair via activating Notch signaling pathway in ovariectomized rats
The purpose was to observe whether valproic acid (VPA) has a positive effect on bone-defect repair via activating the Notch signaling pathway in an OVX rat model. The MC3T3-E1 cells were cocultured with VPA and induced to osteogenesis, and the osteogenic activity was observed by alkaline phosphatase...
Autores principales: | Tao, Zhou-Shan, Li, Tian-Lin, Xu, Hong-Guang, Yang, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702411/ https://www.ncbi.nlm.nih.gov/pubmed/34940936 http://dx.doi.org/10.1007/s10856-021-06627-2 |
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