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The function of the co-chaperone ERdj4 in diverse (patho-)physiological conditions
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces a well-orchestrated cellular response to reduce the protein burden within the ER. This unfolded protein response (UPR) is controlled primarily by three transmembrane proteins, IRE1α, ATF6, and PERK, the activity of which is...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702508/ https://www.ncbi.nlm.nih.gov/pubmed/34950970 http://dx.doi.org/10.1007/s00018-021-04082-4 |