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Sigma-1 Receptor is a Pharmacological Target to Promote Neuroprotection in the SOD1(G93A) ALS Mice

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized by the death of motoneurons (MNs) with a poor prognosis. There is no available cure, thus, novel therapeutic targets are urgently needed. Sigma-1 receptor (Sig-1R) has been reported as a target to treat experimental mo...

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Detalles Bibliográficos
Autores principales: Gaja-Capdevila, Núria, Hernández, Neus, Navarro, Xavier, Herrando-Grabulosa, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702863/
https://www.ncbi.nlm.nih.gov/pubmed/34955848
http://dx.doi.org/10.3389/fphar.2021.780588