Phasor Histone FLIM-FRET Microscopy Maps Nuclear-Wide Nanoscale Chromatin Architecture With Respect to Genetically Induced DNA Double-Strand Breaks

A DNA double-strand break (DSB) takes place in the context of chromatin, and there is increasing evidence for chromatin structure to play a functional role in DSB signaling and repair. Thus, there is an emerging need for quantitative microscopy methods that can directly measure chromatin network arc...

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Detalles Bibliográficos
Autores principales: Lou, Jieqiong, Solano, Ashleigh, Liang, Zhen, Hinde, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702996/
https://www.ncbi.nlm.nih.gov/pubmed/34956323
http://dx.doi.org/10.3389/fgene.2021.770081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702996/
https://www.ncbi.nlm.nih.gov/pubmed/34956323
http://dx.doi.org/10.3389/fgene.2021.770081

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