Disruption of Folate Metabolism Causes Poor Alignment and Spacing of Mouse Conceptuses for Multiple Generations

Abnormal uptake or metabolism of folate increases risk of human pregnancy complications, though the mechanism is unclear. Here, we explore how defective folate metabolism influences early development by analysing mice with the hypomorphic Mtrr ( gt ) mutation. MTRR is necessary for methyl group util...

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Detalles Bibliográficos
Autores principales: Wilkinson, Amy L., Menelaou, Katerina, Rakoczy, Joanna, Tan, Xiu S., Watson, Erica D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703036/
https://www.ncbi.nlm.nih.gov/pubmed/34957089
http://dx.doi.org/10.3389/fcell.2021.723978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703036/
https://www.ncbi.nlm.nih.gov/pubmed/34957089
http://dx.doi.org/10.3389/fcell.2021.723978

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