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Disruption of Folate Metabolism Causes Poor Alignment and Spacing of Mouse Conceptuses for Multiple Generations
Abnormal uptake or metabolism of folate increases risk of human pregnancy complications, though the mechanism is unclear. Here, we explore how defective folate metabolism influences early development by analysing mice with the hypomorphic Mtrr ( gt ) mutation. MTRR is necessary for methyl group util...
Autores principales: | Wilkinson, Amy L., Menelaou, Katerina, Rakoczy, Joanna, Tan, Xiu S., Watson, Erica D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703036/ https://www.ncbi.nlm.nih.gov/pubmed/34957089 http://dx.doi.org/10.3389/fcell.2021.723978 |
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