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Metabolic Reprogramming and Cell Adhesion in Acute Leukemia Adaptation to the CNS Niche
Involvement of the Central Nervous System (CNS) in acute leukemia confers poor prognosis and lower overall survival. Existing CNS-directed therapies are associated with a significant risk of short- or long-term toxicities. Leukemic cells can metabolically adapt and survive in the microenvironment of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703109/ https://www.ncbi.nlm.nih.gov/pubmed/34957100 http://dx.doi.org/10.3389/fcell.2021.767510 |