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PDAC as an Immune Evasive Disease: Can 3D Model Systems Aid to Tackle This Clinical Problem?

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a high mortality rate. The presence of a dense desmoplastic stroma rich in fibroblasts, extracellular matrix, and immune cells plays a critical role in disease progression, therapy response and is a distinguishing feature of PDAC....

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Detalles Bibliográficos
Autores principales: Narayanan, Shruthi, Vicent, Silve, Ponz-Sarvisé, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703167/
https://www.ncbi.nlm.nih.gov/pubmed/34957115
http://dx.doi.org/10.3389/fcell.2021.787249