Impact of dose feasibility on the conduct of phase I trials of adoptive cell therapy

BACKGROUND: /Aims: In early-phase cell therapy trials, each dose level being studied is defined by the number of cells infused into the trial participant. The issue of dose feasibility presents itself when the desired number of cells is not reached in the expansion process. Consequently, dose assign...

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Detalles Bibliográficos
Autores principales: Bagley, Evan M., Wages, Nolan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703230/
https://www.ncbi.nlm.nih.gov/pubmed/34988337
http://dx.doi.org/10.1016/j.conctc.2021.100877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703230/
https://www.ncbi.nlm.nih.gov/pubmed/34988337
http://dx.doi.org/10.1016/j.conctc.2021.100877

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