One-Pot Synthesis of Phosphinylphosphonate Derivatives and Their Anti-Tumor Evaluations

This paper reports on the synthesis of new hydroxymethylene-(phosphinyl)phosphonates (HMPPs). A methodology has been developed to propose an optimized one-pot procedure without any intermediate purifications. Various aliphatic and (hetero)aromatic HMPPs were synthesized in good to excellent yields (...

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Detalles Bibliográficos
Autores principales: Dussart-Gautheret, Jade, Deschamp, Julia, Legigan, Thibaut, Monteil, Maelle, Migianu-Griffoni, Evelyne, Lecouvey, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703271/
https://www.ncbi.nlm.nih.gov/pubmed/34946699
http://dx.doi.org/10.3390/molecules26247609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703271/
https://www.ncbi.nlm.nih.gov/pubmed/34946699
http://dx.doi.org/10.3390/molecules26247609

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