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Combination of Antiretroviral Drugs Zidovudine and Efavirenz Impairs Tumor Growths in a Mouse Model of Cancer

LINE1 retrotransposons, which are thought to be the remnants of ancient integrations of retrovirus-like elements, are aberrantly (re)activated in many cancer cells. Due to LINE1-induced alterations in target gene expression and/or chromosomal rearrangements, they may be important drivers of tumorige...

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Detalles Bibliográficos
Autores principales: Schneider, Marcel A., Buzdin, Anton A., Weber, Achim, Clavien, Pierre-Alain, Borger, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703283/
https://www.ncbi.nlm.nih.gov/pubmed/34960665
http://dx.doi.org/10.3390/v13122396