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Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery

Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver remains the major hurdle for the widespread application of siRNA in vivo. Current cationic liposome or polymer-based delivery agents are restricted to the liver and suffer from off-target effects, poor clearance,...

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Detalles Bibliográficos
Autores principales: Yu, Xiaolin, Xue, Lu, Zhao, Jing, Zhao, Shuhua, Wu, Daqing, Liu, Hong Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703291/
https://www.ncbi.nlm.nih.gov/pubmed/34959463
http://dx.doi.org/10.3390/pharmaceutics13122182