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Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery
Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver remains the major hurdle for the widespread application of siRNA in vivo. Current cationic liposome or polymer-based delivery agents are restricted to the liver and suffer from off-target effects, poor clearance,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703291/ https://www.ncbi.nlm.nih.gov/pubmed/34959463 http://dx.doi.org/10.3390/pharmaceutics13122182 |