2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity

The pharmacological inhibition of soluble epoxide hydrolase (sEH) has been suggested as a potential therapy for the treatment of pain and inflammatory diseases through the stabilization of endogenous epoxyeicosatrienoic acids. Numerous potent sEH inhibitors (sEHI) have been developed, however many c...

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Detalles Bibliográficos
Autores principales: Martín-López, Juan, Codony, Sandra, Bartra, Clara, Morisseau, Christophe, Loza, María Isabel, Sanfeliu, Coral, Hammock, Bruce D., Brea, José, Vázquez, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703317/
https://www.ncbi.nlm.nih.gov/pubmed/34959721
http://dx.doi.org/10.3390/ph14121323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703317/
https://www.ncbi.nlm.nih.gov/pubmed/34959721
http://dx.doi.org/10.3390/ph14121323

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