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2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
The pharmacological inhibition of soluble epoxide hydrolase (sEH) has been suggested as a potential therapy for the treatment of pain and inflammatory diseases through the stabilization of endogenous epoxyeicosatrienoic acids. Numerous potent sEH inhibitors (sEHI) have been developed, however many c...
Autores principales: | Martín-López, Juan, Codony, Sandra, Bartra, Clara, Morisseau, Christophe, Loza, María Isabel, Sanfeliu, Coral, Hammock, Bruce D., Brea, José, Vázquez, Santiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703317/ https://www.ncbi.nlm.nih.gov/pubmed/34959721 http://dx.doi.org/10.3390/ph14121323 |
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