Polar Interactions at the Dimer–Dimer Interface of Methionine Adenosyltransferase MAT I Control Tetramerization

Catalytic MATα1 subunits associate into kinetically distinct homo-dimers (MAT III) and homo-tetramers (MAT I) that synthesize S-adenosylmethionine in the adult liver. Pathological reductions in S-adenosylmethionine levels correlate with MAT III accumulation; thus, it is important to know the determi...

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Detalles Bibliográficos
Autores principales: Sánchez-Pérez, Gabino Francisco, Pajares, María Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703375/
https://www.ncbi.nlm.nih.gov/pubmed/34948004
http://dx.doi.org/10.3390/ijms222413206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703375/
https://www.ncbi.nlm.nih.gov/pubmed/34948004
http://dx.doi.org/10.3390/ijms222413206

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