Design and Synthesis of Highly Active Antimycobacterial Mutual Esters of 2-(2-Isonicotinoylhydrazineylidene)propanoic Acid

The combination of two active scaffolds into one molecule represents a proven approach in drug design to overcome microbial drug resistance. We designed and synthesized more lipophilic esters of 2-(2-isonicotinoylhydrazineylidene)propanoic acid, obtained from antitubercular drug isoniazid, with vari...

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Detalles Bibliográficos
Autores principales: Pflégr, Václav, Maixnerová, Jana, Stolaříková, Jiřina, Pál, Adrián, Korduláková, Jana, Trejtnar, František, Vinšová, Jarmila, Krátký, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703412/
https://www.ncbi.nlm.nih.gov/pubmed/34959704
http://dx.doi.org/10.3390/ph14121302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703412/
https://www.ncbi.nlm.nih.gov/pubmed/34959704
http://dx.doi.org/10.3390/ph14121302

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