Tackling the Threat of Cancer Due to Pathobionts Producing Colibactin: Is Mesalamine the Magic Bullet?

Colibactin is a genotoxin produced primarily by Escherichia coli harboring the genomic pks island (pks(+) E. coli). Pks(+) E. coli cause host cell DNA damage, leading to chromosomal instability and gene mutations. The signature of colibactin-induced mutations has been described and found in human co...

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Detalles Bibliográficos
Autores principales: Tang-Fichaux, Min, Branchu, Priscilla, Nougayrède, Jean-Philippe, Oswald, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703417/
https://www.ncbi.nlm.nih.gov/pubmed/34941734
http://dx.doi.org/10.3390/toxins13120897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703417/
https://www.ncbi.nlm.nih.gov/pubmed/34941734
http://dx.doi.org/10.3390/toxins13120897

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