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Tackling the Threat of Cancer Due to Pathobionts Producing Colibactin: Is Mesalamine the Magic Bullet?
Colibactin is a genotoxin produced primarily by Escherichia coli harboring the genomic pks island (pks(+) E. coli). Pks(+) E. coli cause host cell DNA damage, leading to chromosomal instability and gene mutations. The signature of colibactin-induced mutations has been described and found in human co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703417/ https://www.ncbi.nlm.nih.gov/pubmed/34941734 http://dx.doi.org/10.3390/toxins13120897 |