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Unravelling the Interaction of Piperlongumine with the Nucleotide-Binding Domain of HSP70: A Spectroscopic and In Silico Study

Piperlongumine (PPL) is an alkaloid extracted from several pepper species that exhibits anti-inflammatory and anti-carcinogenic properties. Nevertheless, the molecular mode of action of PPL that confers such powerful pharmacological properties remains unknown. From this perspective, spectroscopic me...

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Detalles Bibliográficos
Autores principales: Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, Jones, Alan M., Cornélio, Marinônio Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703466/
https://www.ncbi.nlm.nih.gov/pubmed/34959698
http://dx.doi.org/10.3390/ph14121298