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The Cell Protective Effect of Adenine on Hypoxia–Reoxygenation Injury through PPAR Delta Activation

Ischemia followed by blood supply reperfusion in cardiomyocytes leads to an overproduction of free radicals and a rapid decrease of adenosine triphosphate concentration. The cardioprotective effect of a potential drug, adenine, was evaluated using H9c2 rat cardiomyoblasts. After hypoxia–reoxygenatio...

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Detalles Bibliográficos
Autores principales: Leu, Jyh-Gang, Wang, Chien-Mei, Chen, Chao-Yi, Yang, Yi-Feng, Shih, Chin-Yu, Lin, Jiun-Tsai, Chen, Han-Min, Liang, Yao-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703696/
https://www.ncbi.nlm.nih.gov/pubmed/34947939
http://dx.doi.org/10.3390/life11121408