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Imaging-Guided Delivery of a Hydrophilic Drug to Eukaryotic Cells Based on Its Hydrophobic Ion Pairing with Poly(hexamethylene guanidine) in a Maleated Chitosan Carrier

Imaging-guided delivery is developed for hydrophobic drugs, and to a much lesser extent, hydrophilic ones. In this work we have designed a novel strategy for real-time monitoring of hydrophilic drug delivery. Traditionally, the drug and the dye are covalently attached to a nanocarrier or are electro...

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Detalles Bibliográficos
Autores principales: Zakharenkova, Sofia A., Lebedeva, Marina I., Lebedeva, Alexandra N., Doroshenko, Irina A., Vlasova, Ksenya Yu, Bartoshevich, Anastasiya A., Senyavin, Vladimir M., Abramchuk, Sergey S., Krivtsov, George G., Ezhov, Alexander A., Podrugina, Tatyana A., Klyachko, Natalia L., Beklemishev, Mikhail K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703758/
https://www.ncbi.nlm.nih.gov/pubmed/34946504
http://dx.doi.org/10.3390/molecules26247426