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Imaging-Guided Delivery of a Hydrophilic Drug to Eukaryotic Cells Based on Its Hydrophobic Ion Pairing with Poly(hexamethylene guanidine) in a Maleated Chitosan Carrier
Imaging-guided delivery is developed for hydrophobic drugs, and to a much lesser extent, hydrophilic ones. In this work we have designed a novel strategy for real-time monitoring of hydrophilic drug delivery. Traditionally, the drug and the dye are covalently attached to a nanocarrier or are electro...
Autores principales: | Zakharenkova, Sofia A., Lebedeva, Marina I., Lebedeva, Alexandra N., Doroshenko, Irina A., Vlasova, Ksenya Yu, Bartoshevich, Anastasiya A., Senyavin, Vladimir M., Abramchuk, Sergey S., Krivtsov, George G., Ezhov, Alexander A., Podrugina, Tatyana A., Klyachko, Natalia L., Beklemishev, Mikhail K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703758/ https://www.ncbi.nlm.nih.gov/pubmed/34946504 http://dx.doi.org/10.3390/molecules26247426 |
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