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A Physiologically Based Pharmacokinetic Model for In Vivo Alpha Particle Generators Targeting Neuroendocrine Tumors in Mice

In vivo alpha particle generators have great potential for the treatment of neuroendocrine tumors in alpha-emitter-based peptide receptor radionuclide therapy (α-PRRT). Quantitative pharmacokinetic analyses of the in vivo alpha particle generator and its radioactive decay products are required to ad...

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Detalles Bibliográficos
Autores principales: Zaid, Nouran R. R., Kletting, Peter, Winter, Gordon, Prasad, Vikas, Beer, Ambros J., Glatting, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703774/
https://www.ncbi.nlm.nih.gov/pubmed/34959413
http://dx.doi.org/10.3390/pharmaceutics13122132