Oncogenic NRAS Accelerates Rhabdomyosarcoma Formation When Occurring within a Specific Time Frame during Tumor Development in Mice

In the Ptch+/- mouse model for embryonal rhabdomyosarcoma (ERMS), we recently showed that oncogenic (onc) H-, K- or NRAS mutations do not influence tumor growth when induced at the advanced, full-blown tumor stage. However, when induced at the invisible ERMS precursor stage at 4 weeks of age, tumor...

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Detalles Bibliográficos
Autores principales: Ragab, Nada, Bauer, Julia, Botermann, Dominik S., Uhmann, Anja, Hahn, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703790/
https://www.ncbi.nlm.nih.gov/pubmed/34948179
http://dx.doi.org/10.3390/ijms222413377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703790/
https://www.ncbi.nlm.nih.gov/pubmed/34948179
http://dx.doi.org/10.3390/ijms222413377

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