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Synthesis of (68)Ga-Labeled cNGR-Based Glycopeptides and In Vivo Evaluation by PET Imaging

Tumor hypoxia induces angiogenesis, which is required for tumor cell survival. The aminopeptidase N receptor (APN/CD13) is an excellent marker of angiogenesis since it is overexpressed in angiogenic blood vessels and in tumor cells. Asparagine-glycine-arginine (NGR) peptide analogs bind selectively...

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Detalles Bibliográficos
Autores principales: Gyuricza, Barbara, Szabó, Judit P., Arató, Viktória, Dénes, Noémi, Szűcs, Ágnes, Berta, Katalin, Kis, Adrienn, Szücs, Dániel, Forgács, Viktória, Szikra, Dezső, Kertész, István, Trencsényi, György, Fekete, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703807/
https://www.ncbi.nlm.nih.gov/pubmed/34959383
http://dx.doi.org/10.3390/pharmaceutics13122103