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Synthesis of (68)Ga-Labeled cNGR-Based Glycopeptides and In Vivo Evaluation by PET Imaging
Tumor hypoxia induces angiogenesis, which is required for tumor cell survival. The aminopeptidase N receptor (APN/CD13) is an excellent marker of angiogenesis since it is overexpressed in angiogenic blood vessels and in tumor cells. Asparagine-glycine-arginine (NGR) peptide analogs bind selectively...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703807/ https://www.ncbi.nlm.nih.gov/pubmed/34959383 http://dx.doi.org/10.3390/pharmaceutics13122103 |