Cargando…
Synthesis of (68)Ga-Labeled cNGR-Based Glycopeptides and In Vivo Evaluation by PET Imaging
Tumor hypoxia induces angiogenesis, which is required for tumor cell survival. The aminopeptidase N receptor (APN/CD13) is an excellent marker of angiogenesis since it is overexpressed in angiogenic blood vessels and in tumor cells. Asparagine-glycine-arginine (NGR) peptide analogs bind selectively...
Autores principales: | Gyuricza, Barbara, Szabó, Judit P., Arató, Viktória, Dénes, Noémi, Szűcs, Ágnes, Berta, Katalin, Kis, Adrienn, Szücs, Dániel, Forgács, Viktória, Szikra, Dezső, Kertész, István, Trencsényi, György, Fekete, Anikó |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703807/ https://www.ncbi.nlm.nih.gov/pubmed/34959383 http://dx.doi.org/10.3390/pharmaceutics13122103 |
Ejemplares similares
-
Synthesis of Novel, Dual-Targeting (68)Ga-NODAGA-LacN-E[c(RGDfK)](2) Glycopeptide as a PET Imaging Agent for Cancer Diagnosis
por: Gyuricza, Barbara, et al.
Publicado: (2021) -
Methods for the Determination of Transition Metal Impurities in Cyclotron-Produced Radiometals
por: Forgács, Viktória, et al.
Publicado: (2022) -
Therapeutic Performance Evaluation of (213)Bi-Labelled Aminopeptidase N (APN/CD13)-Affine NGR-Motif ([(213)Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology
por: Képes, Zita, et al.
Publicado: (2023) -
Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of (68)Ga-, (205/206)Bi-, and (177)Lu-Labeled NAPamide-Based Radiopharmaceuticals
por: Szücs, Dániel, et al.
Publicado: (2023) -
Synthesis, Physicochemical, Labeling and In Vivo Characterization of (44)Sc-Labeled DO3AM-NI as a Hypoxia-Sensitive PET Probe
por: Szücs, Dániel, et al.
Publicado: (2022)