Large-Scale Evaluation of Collision Cross Sections to Investigate Blood-Brain Barrier Permeation of Drugs

Successful drug administration to the central nervous system requires accurate adjustment of the drugs’ molecular properties. Therefore, structure-derived descriptors of potential brain therapeutic agents are essential for an early evaluation of pharmacokinetics during drug development. The collisio...

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Detalles Bibliográficos
Autores principales: Guntner, Armin Sebastian, Bögl, Thomas, Mlynek, Franz, Buchberger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703848/
https://www.ncbi.nlm.nih.gov/pubmed/34959422
http://dx.doi.org/10.3390/pharmaceutics13122141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703848/
https://www.ncbi.nlm.nih.gov/pubmed/34959422
http://dx.doi.org/10.3390/pharmaceutics13122141

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