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Cannabidiol-Loaded Mixed Polymeric Micelles of Chitosan/Poly(Vinyl Alcohol) and Poly(Methyl Methacrylate) for Trans-Corneal Delivery

Ocular drug delivery is challenging due to the very short drug residence time and low permeability. In this work, we produce and characterize mucoadhesive mixed polymeric micelles (PMs) made of chitosan (CS) and poly(vinyl alcohol) backbones graft-hydrophobized with short poly(methyl methacrylate) b...

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Detalles Bibliográficos
Autores principales: Sosnik, Alejandro, Shabo, Ronya Ben, Halamish, Hen Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703866/
https://www.ncbi.nlm.nih.gov/pubmed/34959427
http://dx.doi.org/10.3390/pharmaceutics13122142