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Quantification of 15 Antibiotics Widely Used in the Critical Care Unit with a LC-MS/MS System: An Easy Method to Perform a Daily Therapeutic Drug Monitoring

Potential under- or overdose of antibiotics may occur in intensive care units due to high variability in plasma concentrations. The risk is either treatment failure or toxicity. Thus, therapeutic drug monitoring of antibiotics may guide dosing adjustment, maximising antibacterial efficacy and minimi...

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Detalles Bibliográficos
Autores principales: Feliu, Catherine, Konecki, Celine, Candau, Tristan, Vautier, Damien, Haudecoeur, Cyril, Gozalo, Claire, Cazaubon, Yoann, Djerada, Zoubir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703964/
https://www.ncbi.nlm.nih.gov/pubmed/34959617
http://dx.doi.org/10.3390/ph14121214