Evaluation of the Central Effects of Systemic Lentiviral-Mediated Leptin Delivery in Streptozotocin-Induced Diabetic Rats

Type 1 diabetes (T1D) is characterized by hyperphagia, hyperglycemia and activation of the hypothalamic–pituitary–adrenal (HPA) axis. We have reported previously that daily leptin injections help to alleviate these symptoms. Therefore, we hypothesized that leptin gene therapy could help to normalize...

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Detalles Bibliográficos
Autores principales: Clark, Kimberly A., Shin, Andrew C., Sirivelu, Madhu P., MohanKumar, Ramya C., Maddineni, Sreenivasa R., Ramachandran, Ramesh, MohanKumar, Puliyur S., MohanKumar, Sheba M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703968/
https://www.ncbi.nlm.nih.gov/pubmed/34947993
http://dx.doi.org/10.3390/ijms222413197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703968/
https://www.ncbi.nlm.nih.gov/pubmed/34947993
http://dx.doi.org/10.3390/ijms222413197

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