A Highly Sensitive Fluorescent Akt Biosensor Reveals Lysosome-Selective Regulation of Lipid Second Messengers and Kinase Activity

[Image: see text] The serine/threonine protein kinase Akt regulates a wide range of cellular functions via phosphorylation of various substrates distributed throughout the cell, including at the plasma membrane and endomembrane compartments. Disruption of compartmentalized Akt signaling underlies th...

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Detalles Bibliográficos
Autores principales: Chen, Mingyuan, Sun, Tengqian, Zhong, Yanghao, Zhou, Xin, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704034/
https://www.ncbi.nlm.nih.gov/pubmed/34963894
http://dx.doi.org/10.1021/acscentsci.1c00919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704034/
https://www.ncbi.nlm.nih.gov/pubmed/34963894
http://dx.doi.org/10.1021/acscentsci.1c00919

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