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Modular Design of High-Brightness pH-Activatable Near-Infrared BODIPY Probes for Noninvasive Fluorescence Detection of Deep-Seated Early Breast Cancer Bone Metastasis: Remarkable Axial Substituent Effect on Performance

[Image: see text] We herein report a series of high-brightness pH-activatable near-infrared (NIR) BODIPY probes for high-contrast intravital imaging of deep-seated early breast cancer bone metastasis by harnessing the axial substituent effect. These probes exhibit tunable pK(a), higher brightness, a...

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Detalles Bibliográficos
Autores principales: Wu, Peng, Zhu, Yu, Liu, Senyao, Xiong, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704040/
https://www.ncbi.nlm.nih.gov/pubmed/34963896
http://dx.doi.org/10.1021/acscentsci.1c01066