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Comparing Native Crystal Structures and AlphaFold2 Predicted Water-Soluble G Protein-Coupled Receptor QTY Variants

Accurate predictions of 3-dimensional protein structures by AlphaFold2 is a game-changer for biology, especially for structural biology. Here we present the studies of several native chemokine receptors including CCR5, CCR9, CXCR2 and CXCR4 determined by X-ray crystallography, and their water-solubl...

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Detalles Bibliográficos
Autores principales: Skuhersky, Michael A., Tao, Fei, Qing, Rui, Smorodina, Eva, Jin, David, Zhang, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704054/
https://www.ncbi.nlm.nih.gov/pubmed/34947816
http://dx.doi.org/10.3390/life11121285