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Functional Gallic Acid-Based Dendrimers as Synthetic Nanotools to Remodel Amyloid-β-42 into Noncytotoxic Forms

[Image: see text] The self-assembly of amyloid-β (Aβ) generates cytotoxic oligomers linked to the onset and progression of Alzheimer’s disease (AD). As many fundamental molecular pathways that control Aβ aggregation are yet to be unraveled, an important strategy to control Aβ cytotoxicity is the dev...

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Detalles Bibliográficos
Autores principales: Araújo, Ana R., Correa, Juan, Dominguez-Arca, Vicente, Reis, Rui L., Fernandez-Megia, Eduardo, Pires, Ricardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704170/
https://www.ncbi.nlm.nih.gov/pubmed/34874691
http://dx.doi.org/10.1021/acsami.1c17823