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The Autophagy Cargo Receptor SQSTM1 Inhibits Infectious Bursal Disease Virus Infection through Selective Autophagic Degradation of Double-Stranded Viral RNA

Selective autophagy mediates the degradation of cytoplasmic cargos, such as damaged organelles, invading pathogens, and protein aggregates. However, whether it targets double-stranded RNA (dsRNA) of intracellular pathogens is still largely unknown. Here, we show that selective autophagy regulates th...

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Detalles Bibliográficos
Autores principales: Xu, Chenyang, Li, Tongtong, Lei, Jing, Zhang, Yina, Zhou, Jiyong, Hu, Boli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704251/
https://www.ncbi.nlm.nih.gov/pubmed/34960763
http://dx.doi.org/10.3390/v13122494