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Systemic and Intestinal Viral Reservoirs in CD4+ T Cell Subsets in Primary SIV Infection

The HIV reservoir size in target CD4+ T cells during primary infection remains unknown. Here, we sorted peripheral and intestinal CD4+ T cells and quantified the levels of cell-associated SIV RNA and DNA in rhesus macaques within days of SIVmac251 inoculation. As a major target cell of HIV/SIV, CD4+...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Ziani, Widade, Veazey, Ronald S., Xu, Huanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704255/
https://www.ncbi.nlm.nih.gov/pubmed/34960667
http://dx.doi.org/10.3390/v13122398