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The Small-Molecule Wnt Inhibitor ICG-001 Efficiently Inhibits Colorectal Cancer Stemness and Metastasis by Suppressing MEIS1 Expression

Recurrence and metastasis remain major obstacles in colorectal cancer (CRC) treatment. Recent studies suggest that a small subpopulation of cells with a self-renewal ability, called cancer stem-like cells (CSCs), promotes recurrence and metastasis in CRC. Unfortunately, no CSC inhibitor has been dem...

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Detalles Bibliográficos
Autores principales: Choi, Jang-Hyun, Jang, Tae-Young, Jeon, So-El, Kim, Jee-Heun, Lee, Choong-Jae, Yun, Hyeon-Ji, Jung, Ji-Youn, Park, So-Yeon, Nam, Jeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704261/
https://www.ncbi.nlm.nih.gov/pubmed/34948208
http://dx.doi.org/10.3390/ijms222413413