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How the Innate Immune DNA Sensing cGAS–STING Pathway Is Involved in Autophagy

The cGAS–STING pathway is a key component of the innate immune system and exerts crucial roles in the detection of cytosolic DNA and invading pathogens. Accumulating evidence suggests that the intrinsic cGAS–STING pathway not only facilitates the production of type I interferons (IFN-I) and inflamma...

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Detalles Bibliográficos
Autores principales: Zheng, Wanglong, Xia, Nengwen, Zhang, Jiajia, Chen, Nanhua, Meurens, François, Liu, Zongping, Zhu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704322/
https://www.ncbi.nlm.nih.gov/pubmed/34948027
http://dx.doi.org/10.3390/ijms222413232