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The O-Ag Antibody Response to Francisella Is Distinct in Rodents and Higher Animals and Can Serve as a Correlate of Protection

Identifying correlates of protection (COPs) for vaccines against lethal human (Hu) pathogens, such as Francisella tularensis (Ft), is problematic, as clinical trials are currently untenable and the relevance of various animal models can be controversial. Previously, Hu trials with the live vaccine s...

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Detalles Bibliográficos
Autores principales: Shoudy, Lauren E., Namjoshi, Prachi, Giordano, Gabriela, Kumar, Sudeep, Bowling, Jennifer D., Gelhaus, Carl, Barry, Eileen M., Hazlett, Allan J., Hazlett, Brian A., Cooper, Kristine L., Pittman, Phillip R., Reed, Douglas S., Hazlett, Karsten R. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704338/
https://www.ncbi.nlm.nih.gov/pubmed/34959601
http://dx.doi.org/10.3390/pathogens10121646