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The O-Ag Antibody Response to Francisella Is Distinct in Rodents and Higher Animals and Can Serve as a Correlate of Protection
Identifying correlates of protection (COPs) for vaccines against lethal human (Hu) pathogens, such as Francisella tularensis (Ft), is problematic, as clinical trials are currently untenable and the relevance of various animal models can be controversial. Previously, Hu trials with the live vaccine s...
Autores principales: | Shoudy, Lauren E., Namjoshi, Prachi, Giordano, Gabriela, Kumar, Sudeep, Bowling, Jennifer D., Gelhaus, Carl, Barry, Eileen M., Hazlett, Allan J., Hazlett, Brian A., Cooper, Kristine L., Pittman, Phillip R., Reed, Douglas S., Hazlett, Karsten R. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704338/ https://www.ncbi.nlm.nih.gov/pubmed/34959601 http://dx.doi.org/10.3390/pathogens10121646 |
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