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The Linoleic Acid Content of the Stratum Corneum of Ichthyotic Golden Retriever Dogs Is Reduced as Compared to Healthy Dogs and a Significant Part Is Oxidized in Both Free and Esterified Forms

Golden Retrievers may suffer from Pnpl1-related inherited ichthyosis. Our study shows that in the stratum corneum (SC) of ichthyotic dogs, linoleic acid (LA) is also present in the form of 9-keto-octadecadienoic acid (9-KODE) instead of the acylacid form as in normal dogs. The fatty acids purified f...

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Detalles Bibliográficos
Autores principales: Popa, Iuliana, Solgadi, Audrey, Pin, Didier, Watson, Adrian L., Haftek, Marek, Portoukalian, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704365/
https://www.ncbi.nlm.nih.gov/pubmed/34940561
http://dx.doi.org/10.3390/metabo11120803