Systematic review and meta-analysis of PD-L1 expression discordance between primary tumor and lung cancer brain metastasis

BACKGROUND: Novel immunotherapeutic strategies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis are often administered when metastatic tumors show PD-L1 positivity, even in the setting of lung cancer brain metastasis (LCBM). However, biological differences...

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Detalles Bibliográficos
Autores principales: Tonse, Raees, Rubens, Muni, Appel, Haley, Tom, Martin C, Hall, Matthew D, Odia, Yazmin, McDermott, Michael W, Ahluwalia, Manmeet S, Mehta, Minesh P, Kotecha, Rupesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704382/
https://www.ncbi.nlm.nih.gov/pubmed/34988451
http://dx.doi.org/10.1093/noajnl/vdab166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704382/
https://www.ncbi.nlm.nih.gov/pubmed/34988451
http://dx.doi.org/10.1093/noajnl/vdab166

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