Matrix Metalloproteinase-2 Inhibition in Acute Ischemia-Reperfusion Heart Injury—Cardioprotective Properties of Carvedilol

Matrix metalloproteinase 2 (MMP-2) is activated in hearts upon ischemia-reperfusion (IR) injury and cleaves sarcomeric proteins. It was shown that carvedilol and nebivolol reduced the activity of different MMPs. Hence, we hypothesized that they could reduce MMPs activation in myocytes, and therefore...

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Detalles Bibliográficos
Autores principales: Skrzypiec-Spring, Monika, Urbaniak, Joanna, Sapa-Wojciechowska, Agnieszka, Pietkiewicz, Jadwiga, Orda, Alina, Karolko, Bożena, Danielewicz, Regina, Bil-Lula, Iwona, Woźniak, Mieczysław, Schulz, Richard, Szeląg, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704387/
https://www.ncbi.nlm.nih.gov/pubmed/34959676
http://dx.doi.org/10.3390/ph14121276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704387/
https://www.ncbi.nlm.nih.gov/pubmed/34959676
http://dx.doi.org/10.3390/ph14121276

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